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An hour-specific transcutaneous bilirubin nomogram for Mongolian neonates

Transcutaneous bilirubin (TcB) nomograms have been developed for different populations. However, the TcB level, rate of rise and peak varies among countries and ethnicities. The aim of this study was to establish an hour-specific TcB nomogram for healthy term and late preterm Mongolian neonates duri...

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Autores principales: Akahira-Azuma, Moe, Yonemoto, Naohiro, Mori, Rintaro, Hosokawa, Shinichi, Matsushita, Takeji, Sukhbat, Khulan, Nansal, Gerelmaa, Bavuusuren, Bayasgalantai, Shonkhuuz, Enkhtur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575357/
https://www.ncbi.nlm.nih.gov/pubmed/25869495
http://dx.doi.org/10.1007/s00431-015-2536-2
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author Akahira-Azuma, Moe
Yonemoto, Naohiro
Mori, Rintaro
Hosokawa, Shinichi
Matsushita, Takeji
Sukhbat, Khulan
Nansal, Gerelmaa
Bavuusuren, Bayasgalantai
Shonkhuuz, Enkhtur
author_facet Akahira-Azuma, Moe
Yonemoto, Naohiro
Mori, Rintaro
Hosokawa, Shinichi
Matsushita, Takeji
Sukhbat, Khulan
Nansal, Gerelmaa
Bavuusuren, Bayasgalantai
Shonkhuuz, Enkhtur
author_sort Akahira-Azuma, Moe
collection PubMed
description Transcutaneous bilirubin (TcB) nomograms have been developed for different populations. However, the TcB level, rate of rise and peak varies among countries and ethnicities. The aim of this study was to establish an hour-specific TcB nomogram for healthy term and late preterm Mongolian neonates during the first 144 h after birth. A total of 5084 TcB measurements from 1297 healthy neonates (gestational age ≥35 weeks, birth weight ≥2000 g) were obtained from October 2012 to October 2013. All measurements were performed using the Jaundice Meter, the JM-103 at 6 to 144 postnatal hours. Mongolian infants had the following characteristics: 27.1 % were delivered by cesarean section, 17.8 % had a birth weight >4000 g, and >90 % were being breastfed. TcB percentiles for each designated time point were calculated for the development of an hour-specific nomogram. TcB levels increased most rapidly in the first 24 h and less rapidly from 24 to 78 h, reaching a plateau after 78 h for the 50th percentile. TcB levels of Mongolian neonates for each time point were higher than those of previous studies. Conclusion: The higher values of the TcB nomogram for Mongolian neonates may be due to their Asian ethnicity and exclusive breastfeeding.
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spelling pubmed-45753572015-09-23 An hour-specific transcutaneous bilirubin nomogram for Mongolian neonates Akahira-Azuma, Moe Yonemoto, Naohiro Mori, Rintaro Hosokawa, Shinichi Matsushita, Takeji Sukhbat, Khulan Nansal, Gerelmaa Bavuusuren, Bayasgalantai Shonkhuuz, Enkhtur Eur J Pediatr Original Article Transcutaneous bilirubin (TcB) nomograms have been developed for different populations. However, the TcB level, rate of rise and peak varies among countries and ethnicities. The aim of this study was to establish an hour-specific TcB nomogram for healthy term and late preterm Mongolian neonates during the first 144 h after birth. A total of 5084 TcB measurements from 1297 healthy neonates (gestational age ≥35 weeks, birth weight ≥2000 g) were obtained from October 2012 to October 2013. All measurements were performed using the Jaundice Meter, the JM-103 at 6 to 144 postnatal hours. Mongolian infants had the following characteristics: 27.1 % were delivered by cesarean section, 17.8 % had a birth weight >4000 g, and >90 % were being breastfed. TcB percentiles for each designated time point were calculated for the development of an hour-specific nomogram. TcB levels increased most rapidly in the first 24 h and less rapidly from 24 to 78 h, reaching a plateau after 78 h for the 50th percentile. TcB levels of Mongolian neonates for each time point were higher than those of previous studies. Conclusion: The higher values of the TcB nomogram for Mongolian neonates may be due to their Asian ethnicity and exclusive breastfeeding. Springer Berlin Heidelberg 2015-04-14 2015 /pmc/articles/PMC4575357/ /pubmed/25869495 http://dx.doi.org/10.1007/s00431-015-2536-2 Text en © The Author(s) 2015 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Article
Akahira-Azuma, Moe
Yonemoto, Naohiro
Mori, Rintaro
Hosokawa, Shinichi
Matsushita, Takeji
Sukhbat, Khulan
Nansal, Gerelmaa
Bavuusuren, Bayasgalantai
Shonkhuuz, Enkhtur
An hour-specific transcutaneous bilirubin nomogram for Mongolian neonates
title An hour-specific transcutaneous bilirubin nomogram for Mongolian neonates
title_full An hour-specific transcutaneous bilirubin nomogram for Mongolian neonates
title_fullStr An hour-specific transcutaneous bilirubin nomogram for Mongolian neonates
title_full_unstemmed An hour-specific transcutaneous bilirubin nomogram for Mongolian neonates
title_short An hour-specific transcutaneous bilirubin nomogram for Mongolian neonates
title_sort hour-specific transcutaneous bilirubin nomogram for mongolian neonates
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575357/
https://www.ncbi.nlm.nih.gov/pubmed/25869495
http://dx.doi.org/10.1007/s00431-015-2536-2
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