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Enhanced activity of NLRP3 inflammasome in peripheral blood cells of patients with active rheumatoid arthritis

INTRODUCTION: Interleukin-1β (IL-1β) is a major inflammatory cytokine, produced predominantly by innate immune cells through NLRP3-inflammasome activation. Both intrinsic and extrinsic danger signals may activate NLRP3. Genetic variations in NLRP3-inflammasome components have been reported to influe...

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Detalles Bibliográficos
Autores principales:	Choulaki, Christianna, Papadaki, Garyfallia, Repa, Argyro, Kampouraki, Eleni, Kambas, Konstantinos, Ritis, Konstantinos, Bertsias, George, Boumpas, Dimitrios T., Sidiropoulos, Prodromos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575443/ https://www.ncbi.nlm.nih.gov/pubmed/26385789 http://dx.doi.org/10.1186/s13075-015-0775-2

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