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RNA interferences targeting the Fanconi anemia/BRCA pathway upstream genes reverse cisplatin resistance in drug-resistant lung cancer cells

BACKGROUND: Cisplatin is one of the most commonly used chemotherapy agent for lung cancer. The therapeutic efficacy of cisplatin is limited by the development of resistance. In this study, we test the effect of RNA interference (RNAi) targeting Fanconi anemia (FA)/BRCA pathway upstream genes on the...

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Detalles Bibliográficos
Autores principales:	Dai, Chun-Hua, Li, Jian, Chen, Ping, Jiang, He-Guo, Wu, Ming, Chen, Yong-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575453/ https://www.ncbi.nlm.nih.gov/pubmed/26385482 http://dx.doi.org/10.1186/s12929-015-0185-4

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