Successful pregnancy following the transfer of vitrified blastocyst which developed from poor quality embryos on day 3

BACKGROUND: The selection of pre-embryos for transferred is based on morphological appearance. But some poor quality cleaved embryos also can be cultured to the blastocyst stage and implanted. OBJECTIVE: To assess the clinical pregnancy outcomes of blastocyst transfer which developed from poor quali...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-jian, Yang, Ye-zhou, Min, Li-hua, Lv, Qun, Bai, Pin, Li, Xiao-jie, Liao, Mei-xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research and Clinical Center for Infertility 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575755/
https://www.ncbi.nlm.nih.gov/pubmed/26396565
Descripción
Sumario:BACKGROUND: The selection of pre-embryos for transferred is based on morphological appearance. But some poor quality cleaved embryos also can be cultured to the blastocyst stage and implanted. OBJECTIVE: To assess the clinical pregnancy outcomes of blastocyst transfer which developed from poor quality embryos. MATERIALS AND METHODS: A total of 109 cleaved embryos with poor quality were cultured to day 5/day 6 and 27 (24.8%) blastocysts were collected from the 15 cycles/patients undergoing conventional IVF. All the blastocysts were cooling with fast-freezing. Then the blastocysts were warmed for transfer. RESULTS: All of 25 vitrified blastocysts (92.6%) survived after warming and were transferred to 15 patients. Five of the women became pregnant. CONCLUSION: Our results suggest that vitrified human day 5/day 6 blastocyst transfer which develop from poor quality embryo at day 3 can contribute to increasing cumulative pregnancy rates in assisted reproduction.

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