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Evaluation of the effect of oral ritodrine on implantation rate in in-vitro fertilization-embryo transfer cycles
BACKGROUND: Pregnancy rate with IVF cycle is almost 22%. Many investigations perform to increase this rate in IVF. Various factors affect the result of IVF cycles. One of these factors could be uterine contractions that expel transferred embryo. Ritodrine is a beta mimetic agent that can block and d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research and Clinical Center for Infertility
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575760/ https://www.ncbi.nlm.nih.gov/pubmed/26396570 |
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author | Rabiee, Soghra Farimani, Marziyyeh Ahmadi, Maryam |
author_facet | Rabiee, Soghra Farimani, Marziyyeh Ahmadi, Maryam |
author_sort | Rabiee, Soghra |
collection | PubMed |
description | BACKGROUND: Pregnancy rate with IVF cycle is almost 22%. Many investigations perform to increase this rate in IVF. Various factors affect the result of IVF cycles. One of these factors could be uterine contractions that expel transferred embryo. Ritodrine is a beta mimetic agent that can block and decrease uterine contractions. OBJECTIVE: The objective of this study was to determine ritodrine effectiveness for increasing the implantation rate in IVF cycles, and its probable mechanisms in decreasing uterine contractions as well. MATERIALS AND METHODS: A total of 100 patients of IVF-ET cycles were divided randomly in two groups in a university hospital, Hamadan, Iran. The case group were prescribed ritodrine 10 mg / bid orally after oocyte retrieval until 10 days. The control group didn’t received ridotrine. RESULTS: In ritodrine group 14% of patients and in control group 16% had positive β-hCG test (p-value>0.5). CONCLUSION: Ritodrine did not improve the implantation rate in IVF-ET cycles. |
format | Online Article Text |
id | pubmed-4575760 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Research and Clinical Center for Infertility |
record_format | MEDLINE/PubMed |
spelling | pubmed-45757602015-09-22 Evaluation of the effect of oral ritodrine on implantation rate in in-vitro fertilization-embryo transfer cycles Rabiee, Soghra Farimani, Marziyyeh Ahmadi, Maryam Iran J Reprod Med Original Article BACKGROUND: Pregnancy rate with IVF cycle is almost 22%. Many investigations perform to increase this rate in IVF. Various factors affect the result of IVF cycles. One of these factors could be uterine contractions that expel transferred embryo. Ritodrine is a beta mimetic agent that can block and decrease uterine contractions. OBJECTIVE: The objective of this study was to determine ritodrine effectiveness for increasing the implantation rate in IVF cycles, and its probable mechanisms in decreasing uterine contractions as well. MATERIALS AND METHODS: A total of 100 patients of IVF-ET cycles were divided randomly in two groups in a university hospital, Hamadan, Iran. The case group were prescribed ritodrine 10 mg / bid orally after oocyte retrieval until 10 days. The control group didn’t received ridotrine. RESULTS: In ritodrine group 14% of patients and in control group 16% had positive β-hCG test (p-value>0.5). CONCLUSION: Ritodrine did not improve the implantation rate in IVF-ET cycles. Research and Clinical Center for Infertility 2011 /pmc/articles/PMC4575760/ /pubmed/26396570 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Rabiee, Soghra Farimani, Marziyyeh Ahmadi, Maryam Evaluation of the effect of oral ritodrine on implantation rate in in-vitro fertilization-embryo transfer cycles |
title | Evaluation of the effect of oral ritodrine on implantation rate in in-vitro fertilization-embryo transfer cycles |
title_full | Evaluation of the effect of oral ritodrine on implantation rate in in-vitro fertilization-embryo transfer cycles |
title_fullStr | Evaluation of the effect of oral ritodrine on implantation rate in in-vitro fertilization-embryo transfer cycles |
title_full_unstemmed | Evaluation of the effect of oral ritodrine on implantation rate in in-vitro fertilization-embryo transfer cycles |
title_short | Evaluation of the effect of oral ritodrine on implantation rate in in-vitro fertilization-embryo transfer cycles |
title_sort | evaluation of the effect of oral ritodrine on implantation rate in in-vitro fertilization-embryo transfer cycles |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575760/ https://www.ncbi.nlm.nih.gov/pubmed/26396570 |
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