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Therapeutic Plasmapheresis Enabling Radioactive Iodine Treatment in a Patient with Thyrotoxicosis
Therapeutic plasma exchange (TPE) is one possible treatment for patients resistant to conventional antithyroid drugs or requiring urgent attention for thyrotoxicosis. We report a 35-yr-old man with thyrotoxicosis, ultimately attributed to Graves' disease in whom antithyroid drug used initially...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Medical Sciences
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575946/ https://www.ncbi.nlm.nih.gov/pubmed/26425054 http://dx.doi.org/10.3346/jkms.2015.30.10.1531 |
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author | Min, Se Hee Phung, Anita Oh, Tae Jung Han, Kyou-Sup Kim, Man Jin Kim, Jee Min Lee, Ji hyun Park, Young Joo |
author_facet | Min, Se Hee Phung, Anita Oh, Tae Jung Han, Kyou-Sup Kim, Man Jin Kim, Jee Min Lee, Ji hyun Park, Young Joo |
author_sort | Min, Se Hee |
collection | PubMed |
description | Therapeutic plasma exchange (TPE) is one possible treatment for patients resistant to conventional antithyroid drugs or requiring urgent attention for thyrotoxicosis. We report a 35-yr-old man with thyrotoxicosis, ultimately attributed to Graves' disease in whom antithyroid drug used initially was soon discontinued, due to abnormal liver function, and replaced by Lugol's solution. Three weeks later, an escape phenomenon (to Lugol's solution) was apparent, so we performed TPE to control the thyrotoxicosis. Two courses of TPE by a centrifugal type machine resulted in diminished levels of thyroid hormone levels, which then rebounded after another two courses of membrane filtration type TPE. However, the patient could be treated with radioactive iodine therapy without any complications at present. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-4575946 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-45759462015-10-01 Therapeutic Plasmapheresis Enabling Radioactive Iodine Treatment in a Patient with Thyrotoxicosis Min, Se Hee Phung, Anita Oh, Tae Jung Han, Kyou-Sup Kim, Man Jin Kim, Jee Min Lee, Ji hyun Park, Young Joo J Korean Med Sci Case Report Therapeutic plasma exchange (TPE) is one possible treatment for patients resistant to conventional antithyroid drugs or requiring urgent attention for thyrotoxicosis. We report a 35-yr-old man with thyrotoxicosis, ultimately attributed to Graves' disease in whom antithyroid drug used initially was soon discontinued, due to abnormal liver function, and replaced by Lugol's solution. Three weeks later, an escape phenomenon (to Lugol's solution) was apparent, so we performed TPE to control the thyrotoxicosis. Two courses of TPE by a centrifugal type machine resulted in diminished levels of thyroid hormone levels, which then rebounded after another two courses of membrane filtration type TPE. However, the patient could be treated with radioactive iodine therapy without any complications at present. GRAPHICAL ABSTRACT: [Image: see text] The Korean Academy of Medical Sciences 2015-10 2015-09-12 /pmc/articles/PMC4575946/ /pubmed/26425054 http://dx.doi.org/10.3346/jkms.2015.30.10.1531 Text en © 2015 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Min, Se Hee Phung, Anita Oh, Tae Jung Han, Kyou-Sup Kim, Man Jin Kim, Jee Min Lee, Ji hyun Park, Young Joo Therapeutic Plasmapheresis Enabling Radioactive Iodine Treatment in a Patient with Thyrotoxicosis |
title | Therapeutic Plasmapheresis Enabling Radioactive Iodine Treatment in a Patient with Thyrotoxicosis |
title_full | Therapeutic Plasmapheresis Enabling Radioactive Iodine Treatment in a Patient with Thyrotoxicosis |
title_fullStr | Therapeutic Plasmapheresis Enabling Radioactive Iodine Treatment in a Patient with Thyrotoxicosis |
title_full_unstemmed | Therapeutic Plasmapheresis Enabling Radioactive Iodine Treatment in a Patient with Thyrotoxicosis |
title_short | Therapeutic Plasmapheresis Enabling Radioactive Iodine Treatment in a Patient with Thyrotoxicosis |
title_sort | therapeutic plasmapheresis enabling radioactive iodine treatment in a patient with thyrotoxicosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4575946/ https://www.ncbi.nlm.nih.gov/pubmed/26425054 http://dx.doi.org/10.3346/jkms.2015.30.10.1531 |
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