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Rapid, Semiquantitative Assay To Discriminate among Compounds with Activity against Replicating or Nonreplicating Mycobacterium tuberculosis

The search for drugs that can kill replicating and nonreplicating Mycobacterium tuberculosis faces practical bottlenecks. Measurement of CFU and discrimination of bacteriostatic from bactericidal activity are costly in compounds, supplies, labor, and time. Testing compounds against M. tuberculosis u...

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Detalles Bibliográficos
Autores principales: Gold, Ben, Roberts, Julia, Ling, Yan, Quezada, Landys Lopez, Glasheen, Jou, Ballinger, Elaine, Somersan-Karakaya, Selin, Warrier, Thulasi, Warren, J. David, Nathan, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576094/
https://www.ncbi.nlm.nih.gov/pubmed/26239979
http://dx.doi.org/10.1128/AAC.00803-15

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