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Structure, Dynamics, and Allosteric Potential of Ionotropic Glutamate Receptor N-Terminal Domains

Ionotropic glutamate receptors (iGluRs) are tetrameric cation channels that mediate synaptic transmission and plasticity. They have a unique modular architecture with four domains: the intracellular C-terminal domain (CTD) that is involved in synaptic targeting, the transmembrane domain (TMD) that f...

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Detalles Bibliográficos
Autores principales: Krieger, James, Bahar, Ivet, Greger, Ingo H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576161/
https://www.ncbi.nlm.nih.gov/pubmed/26255587
http://dx.doi.org/10.1016/j.bpj.2015.06.061