The Immune Adaptor SLP-76 Binds to SUMO-RANGAP1 at Nuclear Pore Complex Filaments to Regulate Nuclear Import of Transcription Factors in T Cells

While immune cell adaptors regulate proximal T cell signaling, direct regulation of the nuclear pore complex (NPC) has not been reported. NPC has cytoplasmic filaments composed of RanGAP1 and RanBP2 with the potential to interact with cytoplasmic mediators. Here, we show that the immune cell adaptor...

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Detalles Bibliográficos
Autores principales: Liu, Hebin, Schneider, Helga, Recino, Asha, Richardson, Christine, Goldberg, Martin W., Rudd, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576164/
https://www.ncbi.nlm.nih.gov/pubmed/26321253
http://dx.doi.org/10.1016/j.molcel.2015.07.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576164/
https://www.ncbi.nlm.nih.gov/pubmed/26321253
http://dx.doi.org/10.1016/j.molcel.2015.07.015

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