Cargando…
CCR5 Targeted Cell Therapy for HIV and Prevention of Viral Escape
Allogeneic transplantation with CCR5-delta 32 (CCR5-d32) homozygous stem cells in an HIV infected individual in 2008, led to a sustained virus control and probably eradication of HIV. Since then there has been a high degree of interest to translate this approach to a wider population. There are two...
Autores principales: | Hütter, Gero, Bodor, Josef, Ledger, Scott, Boyd, Maureen, Millington, Michelle, Tsie, Marlene, Symonds, Geoff |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576177/ https://www.ncbi.nlm.nih.gov/pubmed/26225991 http://dx.doi.org/10.3390/v7082816 |
Ejemplares similares
-
CCR5 as a Natural and Modulated Target for Inhibition of HIV
por: Burke, Bryan P., et al.
Publicado: (2013) -
Clearing the HIV reservoir by transplanting CCR5 deficient stem cells
por: Hütter, Gero
Publicado: (2011) -
Eradication of HIV by Transplantation of CCR5-Deficient Hematopoietic Stem Cells
por: Hütter, Gero, et al.
Publicado: (2011) -
Preclinical safety and efficacy of an anti–HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor
por: Wolstein, Orit, et al.
Publicado: (2014) -
Coregulation of HIV-1 dependency factors in individuals heterozygous to the CCR5-delta32 deletion
por: Hütter, Gero, et al.
Publicado: (2013)