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RNA-Dependent RNA Polymerases of Picornaviruses: From the Structure to Regulatory Mechanisms

RNA viruses typically encode their own RNA-dependent RNA polymerase (RdRP) to ensure genome replication within the infected cells. RdRP function is critical not only for the virus life cycle but also for its adaptive potential. The combination of low fidelity of replication and the absence of proofr...

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Detalles Bibliográficos
Autores principales: Ferrer-Orta, Cristina, Ferrero, Diego, Verdaguer, Núria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576190/
https://www.ncbi.nlm.nih.gov/pubmed/26258787
http://dx.doi.org/10.3390/v7082829