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DISTMIX: direct imputation of summary statistics for unmeasured SNPs from mixed ethnicity cohorts
Motivation: To increase the signal resolution for large-scale meta-analyses of genome-wide association studies, genotypes at unmeasured single nucleotide polymorphisms (SNPs) are commonly imputed using large multi-ethnic reference panels. However, the ever increasing size and ethnic diversity of bot...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576696/ https://www.ncbi.nlm.nih.gov/pubmed/26059716 http://dx.doi.org/10.1093/bioinformatics/btv348 |