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Safety issues of current analgesics: an update

Pain represents a complex experience which can be approached by various medicines. Non-opioid and opioid analgesics are the most common drugs used to manage different types of pain. The increased attention nowadays to pain management entailed concomitantly more frequent adverse drug reactions (ADRs)...

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Autores principales: CAZACU, IRINA, MOGOSAN, CRISTINA, LOGHIN, FELICIA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iuliu Hatieganu University of Medicine and Pharmacy 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576793/
https://www.ncbi.nlm.nih.gov/pubmed/26528060
http://dx.doi.org/10.15386/cjmed-413
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author CAZACU, IRINA
MOGOSAN, CRISTINA
LOGHIN, FELICIA
author_facet CAZACU, IRINA
MOGOSAN, CRISTINA
LOGHIN, FELICIA
author_sort CAZACU, IRINA
collection PubMed
description Pain represents a complex experience which can be approached by various medicines. Non-opioid and opioid analgesics are the most common drugs used to manage different types of pain. The increased attention nowadays to pain management entailed concomitantly more frequent adverse drug reactions (ADRs) related to analgesic use. Drug-drug interactions can be sometimes responsible for the adverse effects. However, a significant proportion of analgesic ADRs are preventable, which would avoid patient suffering. In order to draw the attention to analgesics risks and to minimize the negative consequences related to their use, the present review comprises a synthesis of the most important safety issues described in the scientific literature. It highlights the potential risks of the most frequently used analgesic medicines: non-opioid (paracetamol, metamizole, non-steroidal anti-inflammatory drugs) and opioid analgesics. Even if there is a wide experience in their use, they continue to capture attention with safety concerns and with potential risks recently revealed. Acknowledging potential safety problems represents the first step for health professionals in assuring a safe and efficient analgesic treatment with minimum risks to patients. Taking into consideration all medical and environmental factors and carefully monitoring the patients are also essential in preventing and early detecting analgesic ADRs.
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spelling pubmed-45767932015-11-02 Safety issues of current analgesics: an update CAZACU, IRINA MOGOSAN, CRISTINA LOGHIN, FELICIA Clujul Med Review Pain represents a complex experience which can be approached by various medicines. Non-opioid and opioid analgesics are the most common drugs used to manage different types of pain. The increased attention nowadays to pain management entailed concomitantly more frequent adverse drug reactions (ADRs) related to analgesic use. Drug-drug interactions can be sometimes responsible for the adverse effects. However, a significant proportion of analgesic ADRs are preventable, which would avoid patient suffering. In order to draw the attention to analgesics risks and to minimize the negative consequences related to their use, the present review comprises a synthesis of the most important safety issues described in the scientific literature. It highlights the potential risks of the most frequently used analgesic medicines: non-opioid (paracetamol, metamizole, non-steroidal anti-inflammatory drugs) and opioid analgesics. Even if there is a wide experience in their use, they continue to capture attention with safety concerns and with potential risks recently revealed. Acknowledging potential safety problems represents the first step for health professionals in assuring a safe and efficient analgesic treatment with minimum risks to patients. Taking into consideration all medical and environmental factors and carefully monitoring the patients are also essential in preventing and early detecting analgesic ADRs. Iuliu Hatieganu University of Medicine and Pharmacy 2015 2015-04-15 /pmc/articles/PMC4576793/ /pubmed/26528060 http://dx.doi.org/10.15386/cjmed-413 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
spellingShingle Review
CAZACU, IRINA
MOGOSAN, CRISTINA
LOGHIN, FELICIA
Safety issues of current analgesics: an update
title Safety issues of current analgesics: an update
title_full Safety issues of current analgesics: an update
title_fullStr Safety issues of current analgesics: an update
title_full_unstemmed Safety issues of current analgesics: an update
title_short Safety issues of current analgesics: an update
title_sort safety issues of current analgesics: an update
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576793/
https://www.ncbi.nlm.nih.gov/pubmed/26528060
http://dx.doi.org/10.15386/cjmed-413
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