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Insight into the Binding Mode of Agonists of the Nicotinic Acetylcholine Receptor from Calculated Electron Densities

Insect nicotinic acetylcholine receptors (nAChRs) are among the most prominent and most economically important insecticide targets. Thus, an understanding of the modes of binding of respective agonists is important for the design of specific compounds with favorable vertebrate profiles. In the case...

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Detalles Bibliográficos
Autores principales: Beck, Michael E, Gutbrod, Oliver, Matthiesen, Svend
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576818/
https://www.ncbi.nlm.nih.gov/pubmed/26175091
http://dx.doi.org/10.1002/cphc.201500341