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Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock
Small-molecule probes have been playing prominent roles in furthering our understanding of the molecular underpinnings of the circadian clock. We previously discovered a carbazole derivative, KL001 (N-(3-(9H-carbazol-9-yl)-2-hydroxypropyl)-N-(furan-2-ylmethyl)methanesulfonamide), as a stabilizer of...
Autores principales: | Lee, Jae Wook, Hirota, Tsuyoshi, Kumar, Anupriya, Kim, Nam-Jung, Irle, Stephan, Kay, Steve A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576822/ https://www.ncbi.nlm.nih.gov/pubmed/26174033 http://dx.doi.org/10.1002/cmdc.201500260 |
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