TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity

The present paradigms of selective autophagy in mammalian cells cannot fully explain the specificity and selectivity of autophagic degradation. In this paper, we report that a subset of tripartite motif (TRIM) proteins act as specialized receptors for highly specific autophagy (precision autophagy)...

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Detalles Bibliográficos
Autores principales: Kimura, Tomonori, Jain, Ashish, Choi, Seong Won, Mandell, Michael A., Schroder, Kate, Johansen, Terje, Deretic, Vojo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576868/
https://www.ncbi.nlm.nih.gov/pubmed/26347139
http://dx.doi.org/10.1083/jcb.201503023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576868/
https://www.ncbi.nlm.nih.gov/pubmed/26347139
http://dx.doi.org/10.1083/jcb.201503023

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