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Inhibitors of the AAA+ Chaperone p97

It is remarkable that a pathway as ubiquitous as protein quality control can be targeted to treat cancer. Bortezomib, an inhibitor of the proteasome, was first approved by the US Food and Drug Administration (FDA) more than 10 years ago to treat refractory myeloma and later extended to lymphoma. Its...

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Detalles Bibliográficos
Autores principales:	Chapman, Eli, Maksim, Nick, de la Cruz, Fabian, La Clair, James J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4576884/ https://www.ncbi.nlm.nih.gov/pubmed/25685910 http://dx.doi.org/10.3390/molecules20023027

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