Validation of (64)Cu-ATSM damaging DNA via high-LET Auger electron emission

Radioactive copper (II) (diacetyl-bis N4-methylthiosemicarbazone) (Cu-ATSM) isotopes were originally developed for the imaging of hypoxia in tumors. Because the decay of a (64)Cu atom is emitting not only positrons but also Auger electrons, this radionuclide has great potential as a theranostic agen...

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Detalles Bibliográficos
Autores principales: McMillan, Dayton D., Maeda, Junko, Bell, Justin J., Genet, Matthew D., Phoonswadi, Garrett, Mann, Kelly A., Kraft, Susan L., Kitamura, Hisashi, Fujimori, Akira, Yoshii, Yukie, Furukawa, Takako, Fujibayashi, Yasuhisa, Kato, Takamitsu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577009/
https://www.ncbi.nlm.nih.gov/pubmed/26251463
http://dx.doi.org/10.1093/jrr/rrv042

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