Stents Eluting 6-Mercaptopurine Reduce Neointima Formation and Inflammation while Enhancing Strut Coverage in Rabbits

BACKGROUND: The introduction of drug-eluting stents (DES) has dramatically reduced restenosis rates compared with bare metal stents, but in-stent thrombosis remains a safety concern, necessitating prolonged dual anti-platelet therapy. The drug 6-Mercaptopurine (6-MP) has been shown to have beneficia...

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Detalles Bibliográficos
Autores principales: Ruiter, Matthijs S., van Tiel, Claudia M., Doornbos, Albert, Marinković, Goran, Strang, Aart C., Attevelt, Nico J. M., de Waard, Vivian, de Winter, Robbert J., Steendam, Rob, de Vries, Carlie J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577071/
https://www.ncbi.nlm.nih.gov/pubmed/26389595
http://dx.doi.org/10.1371/journal.pone.0138459

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