Cargando…
KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome
Netherton Syndrome (NS) is a rare and severe autosomal recessive skin disease which can be life-threatening in infants. The disease is characterized by extensive skin desquamation, inflammation, allergic manifestations and hair shaft defects. NS is caused by loss-of-function mutations in SPINK5 enco...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577096/ https://www.ncbi.nlm.nih.gov/pubmed/26390218 http://dx.doi.org/10.1371/journal.pgen.1005389 |