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Rounded leaf end effect of multileaf collimator on penumbra width and radiation field offset: an analytical and numerical study
BACKGROUND: Penumbra characteristics play a significant role in dose delivery accuracy for radiation therapy. For treatment planning, penumbra width and radiation field offset strongly influence target dose conformity and organ at risk sparing. METHODS: In this study, we present an analytical and nu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Versita, Warsaw
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577228/ https://www.ncbi.nlm.nih.gov/pubmed/26401137 http://dx.doi.org/10.1515/raon-2015-0023 |
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author | Zhou, Dong Zhang, Hui Ye, Peiqing |
author_facet | Zhou, Dong Zhang, Hui Ye, Peiqing |
author_sort | Zhou, Dong |
collection | PubMed |
description | BACKGROUND: Penumbra characteristics play a significant role in dose delivery accuracy for radiation therapy. For treatment planning, penumbra width and radiation field offset strongly influence target dose conformity and organ at risk sparing. METHODS: In this study, we present an analytical and numerical approach for evaluation of the rounded leaf end effect on penumbra characteristics. Based on the rule of half-value layer, algorithms for leaf position calculation and radiation field offset correction were developed, which were advantageous particularly in dealing with large radius leaf end. Computer simulation was performed based on the Monte Carlo codes of EGSnrc/BEAMnrc, with groups of leaf end radii and source sizes. Data processing technique of curve fitting was employed for deriving penumbra width and radiation field offset. RESULTS: Results showed that penumbra width increased with source size. Penumbra width curves for large radius leaf end were U-shaped. This observation was probably related to the fact that radiation beams penetrated through the proximal and distal leaf sides. In contrast, source size had negligible impact on radiation field offset. Radiation field offsets were found to be constant both for analytical method and numerical simulation. However, the overall resulting values of radiation field offset obtained by analytical method were slightly smaller compared with Monte Carlo simulation. CONCLUSIONS: The method we proposed could provide insight into the investigation of rounded leaf end effects on penumbra characteristics. Penumbra width and radiation field offset calibration should be carefully performed to commission multileaf collimator for intensity modulated radiotherapy. |
format | Online Article Text |
id | pubmed-4577228 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Versita, Warsaw |
record_format | MEDLINE/PubMed |
spelling | pubmed-45772282015-09-23 Rounded leaf end effect of multileaf collimator on penumbra width and radiation field offset: an analytical and numerical study Zhou, Dong Zhang, Hui Ye, Peiqing Radiol Oncol Research Article BACKGROUND: Penumbra characteristics play a significant role in dose delivery accuracy for radiation therapy. For treatment planning, penumbra width and radiation field offset strongly influence target dose conformity and organ at risk sparing. METHODS: In this study, we present an analytical and numerical approach for evaluation of the rounded leaf end effect on penumbra characteristics. Based on the rule of half-value layer, algorithms for leaf position calculation and radiation field offset correction were developed, which were advantageous particularly in dealing with large radius leaf end. Computer simulation was performed based on the Monte Carlo codes of EGSnrc/BEAMnrc, with groups of leaf end radii and source sizes. Data processing technique of curve fitting was employed for deriving penumbra width and radiation field offset. RESULTS: Results showed that penumbra width increased with source size. Penumbra width curves for large radius leaf end were U-shaped. This observation was probably related to the fact that radiation beams penetrated through the proximal and distal leaf sides. In contrast, source size had negligible impact on radiation field offset. Radiation field offsets were found to be constant both for analytical method and numerical simulation. However, the overall resulting values of radiation field offset obtained by analytical method were slightly smaller compared with Monte Carlo simulation. CONCLUSIONS: The method we proposed could provide insight into the investigation of rounded leaf end effects on penumbra characteristics. Penumbra width and radiation field offset calibration should be carefully performed to commission multileaf collimator for intensity modulated radiotherapy. Versita, Warsaw 2015-08-21 /pmc/articles/PMC4577228/ /pubmed/26401137 http://dx.doi.org/10.1515/raon-2015-0023 Text en Copyright © by Association of Radiology & Oncology http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Research Article Zhou, Dong Zhang, Hui Ye, Peiqing Rounded leaf end effect of multileaf collimator on penumbra width and radiation field offset: an analytical and numerical study |
title | Rounded leaf end effect of multileaf collimator on penumbra width and radiation field offset: an analytical and numerical study |
title_full | Rounded leaf end effect of multileaf collimator on penumbra width and radiation field offset: an analytical and numerical study |
title_fullStr | Rounded leaf end effect of multileaf collimator on penumbra width and radiation field offset: an analytical and numerical study |
title_full_unstemmed | Rounded leaf end effect of multileaf collimator on penumbra width and radiation field offset: an analytical and numerical study |
title_short | Rounded leaf end effect of multileaf collimator on penumbra width and radiation field offset: an analytical and numerical study |
title_sort | rounded leaf end effect of multileaf collimator on penumbra width and radiation field offset: an analytical and numerical study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577228/ https://www.ncbi.nlm.nih.gov/pubmed/26401137 http://dx.doi.org/10.1515/raon-2015-0023 |
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