Improvement of fluvastatin bioavailability by loading on nanostructured lipid carriers

The aim of this study is to prepare fluvastatin nanostructured lipid carriers (FLV-NLCs) in order to find an innovative way to alleviate FLV-associated disadvantages. The limitations include poor solubility and extensive first-pass metabolism, resulting in low (30%) bioavailability and short elimina...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Helw, Abdel-Rahim M, Fahmy, Usama A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577263/
https://www.ncbi.nlm.nih.gov/pubmed/26396513
http://dx.doi.org/10.2147/IJN.S91556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577263/
https://www.ncbi.nlm.nih.gov/pubmed/26396513
http://dx.doi.org/10.2147/IJN.S91556

Ejemplares similares