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Improvement of fluvastatin bioavailability by loading on nanostructured lipid carriers

The aim of this study is to prepare fluvastatin nanostructured lipid carriers (FLV-NLCs) in order to find an innovative way to alleviate FLV-associated disadvantages. The limitations include poor solubility and extensive first-pass metabolism, resulting in low (30%) bioavailability and short elimina...

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Detalles Bibliográficos
Autores principales:	El-Helw, Abdel-Rahim M, Fahmy, Usama A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577263/ https://www.ncbi.nlm.nih.gov/pubmed/26396513 http://dx.doi.org/10.2147/IJN.S91556

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