Cargando…

PEP-1-FK506BP12 inhibits matrix metalloproteinase expression in human articular chondrocytes and in a mouse carrageenan-induced arthritis model

The 12 kDa FK506-binding protein (FK506BP12), an immunosuppressor, modulates T cell activation via calcineurin inhibition. In this study, we investigated the ability of PEP-1-FK506BP12, consisting of FK506BP12 fused to the protein transduction domain PEP-1 peptide, to suppress catabolic responses in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hwang, Hyun Sook, Park, In Young, Kim, Dae Won, Choi, Soo Young, Jung, Young Ok, Kim, Hyun Ah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2015
Materias:	Research-Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577291/ https://www.ncbi.nlm.nih.gov/pubmed/25887750 http://dx.doi.org/10.5483/BMBRep.2015.48.7.050

Ejemplares similares

Effects of PEP-1-FK506BP on cyst formation in polycystic kidney disease
por: Jo, Hyo Sang, et al.
Publicado: (2017)

The effects of PEP-1-FK506BP on dry eye disease in a rat model
por: Kim, Dae Won, et al.
Publicado: (2015)

Fenobam promoted the neuroprotective effect of PEP-1-FK506BP following oxidative stress by increasing its transduction efficiency
por: Ahn, Eun Hee, et al.
Publicado: (2013)

Transduced PEP-1-FK506BP ameliorates corneal injury in Botulinum toxin A-induced dry eye mouse model
por: Kim, Dae Won, et al.
Publicado: (2013)

PEP-1-FK506BP inhibits alkali burn-induced corneal inflammation on the rat model of corneal alkali injury
por: Kim, Dae Won, et al.
Publicado: (2015)

The Effect of FK 506 on the Reepithelialization of Superficial Skin Wound
por: Shin, Jeong Min, et al.
Publicado: (2017)

Maculopathy Associated with Tacrolimus (FK 506)
por: Koh, Taehyuk, et al.
Publicado: (2011)

Interactions of FK506 and Rapamycin With FK506 Binding Protein 12 in Opportunistic Human Fungal Pathogens
por: Vellanki, Sandeep, et al.
Publicado: (2020)

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin
Publicado: (1992)

Betulin suppressed interleukin-1β-induced gene expression, secretion and proteolytic activity of matrix metalloproteinase in cultured articular chondrocytes and production of matrix metalloproteinase in the knee joint of rat
por: Ra, Ho Jong, et al.
Publicado: (2017)

Apigenin Regulates Interleukin-1β-Induced Production of Matrix Metalloproteinase Both in the Knee Joint of Rat and in Primary Cultured Articular Chondrocytes
por: Park, Jin Sung, et al.
Publicado: (2016)

Erratum to: Betulin suppressed interleukin-1b-induced gene expression, secretion and proteolytic activity of matrix metalloproteinase in cultured articular chondrocytes and production of matrix metalloproteinase in the knee joint of rat
por: Ra, Ho Jong, et al.
Publicado: (2017)

Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytes in vitro and the production of matrix metalloproteinase-3 in vivo
por: Kang, Dong-Geun, et al.
Publicado: (2017)

Effects of immunosuppressants, FK506 and cyclosporin A, on the osteogenic differentiation of rat mesenchymal stem cells
por: Byun, Yu-Kyung, et al.
Publicado: (2012)

FK506 immunosuppression for submandibular salivary gland allotransplantation in rabbit
por: Almansoori, Akram Abdo, et al.
Publicado: (2020)

FK506 reduces calpain-regulated calcineurin activity in both the cytoplasm and the nucleus
por: Lee, Sun Hee, et al.
Publicado: (2014)

FK506 and Lactobacillus acidophilus ameliorate acute graft-versus-host disease by modulating the T helper 17/regulatory T-cell balance
por: Beak, Jin-Ah, et al.
Publicado: (2022)

Structure-Guided Synthesis of FK506 and FK520 Analogs with Increased Selectivity Exhibit In Vivo Therapeutic Efficacy against Cryptococcus
por: Hoy, Michael J., et al.
Publicado: (2022)

Effects of FK506 on Ca(2+) Release Channels (Review)
por: Ozawa, Terutaka
Publicado: (2008)

Molecular Evolution of the Vertebrate FK506 Binding Protein 25
por: Liu, Fei, et al.
Publicado: (2014)

FK506 attenuates thymic output in patients with myasthenia gravis
por: Mitsui, Takao, et al.
Publicado: (2013)

Role of FK506-sensitive signals in asthmatic lung inflammation
por: Tomiaki, Chihiro, et al.
Publicado: (2022)

FK506-Binding Protein 2 Participates in Proinsulin Folding
por: Hoefner, Carolin, et al.
Publicado: (2023)

49. Recruited Macrophages are Required for Neuroenhancing Effects of Fk506
por: Broberg, Curtis, et al.
Publicado: (2023)

Advancing Nerve Regeneration: Translational Perspectives of Tacrolimus (FK506)
por: Daeschler, Simeon C., et al.
Publicado: (2023)

FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury
por: Lee, Bohm, et al.
Publicado: (2022)

Protective effect of Korean Red Ginseng against FK506-induced damage in LLC-PK1 cells
por: Lee, Dahae, et al.
Publicado: (2017)

Fibronectin fragment-induced expression of matrix metalloproteinases is mediated by MyD88-dependent TLR-2 signaling pathway in human chondrocytes
por: Hwang, Hyun Sook, et al.
Publicado: (2015)

Mithramycin downregulates proinflammatory cytokine-induced matrix metalloproteinase gene expression in articular chondrocytes
por: Liacini, Abdelhamid, et al.
Publicado: (2005)

Isoliquiritigenin Inhibits IL-1β-Induced Production of Matrix Metalloproteinase in Articular Chondrocytes
por: Zhang, Lei, et al.
Publicado: (2018)

An improved reversibly dimerizing mutant of the FK506-binding protein FKBP
por: Barrero, Juan J., et al.
Publicado: (2016)

Abstract 134: FK506 Delivering Conduit For Peripheral Nerve Regeneration
por: Labroo, Pratima, et al.
Publicado: (2017)

Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35
por: Atack, Thomas C., et al.
Publicado: (2020)

FK506 Attenuated Pilocarpine-Induced Epilepsy by Reducing Inflammation in Rats
por: Wang, Aihua, et al.
Publicado: (2019)

FK506 increases susceptibility to musculoskeletal infection in a rodent model
por: Shiels, Stefanie M., et al.
Publicado: (2022)

Optimization of the precursor supply for an enhanced FK506 production in Streptomyces tsukubaensis
por: Schulz, Susann, et al.
Publicado: (2022)

Development of Non-Immunosuppressive FK506 Derivatives as Antifungal and Neurotrophic Agents
por: Jung, Jin A, et al.
Publicado: (2020)

Inhibition of the Expression of Matrix Metalloproteinases in Articular Chondrocytes by Resveratrol through Affecting Nuclear Factor-Kappa B Signaling Pathway
por: Kang, Dong-Geun, et al.
Publicado: (2018)

FK506-binding protein 51 is a possible novel tumoral marker
por: Romano, S, et al.
Publicado: (2010)

Genome-Wide Screening for Genes Associated with FK506 Sensitivity in Fission Yeast
por: Ma, Yan, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_tl2u9kb0h90um1r8rqesvqda29