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Microsphere-Based Rapamycin Delivery, Systemic Versus Local Administration in a Rat Model of Renal Ischemia/Reperfusion Injury

PURPOSE: The increasing prevalence and treatment costs of kidney diseases call for innovative therapeutic strategies that prevent disease progression at an early stage. We studied a novel method of subcapsular injection of monodisperse microspheres, to use as a local delivery system of drugs to the...

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Detalles Bibliográficos
Autores principales: Zandstra, Jurjen, van Beuge, Marike M., Zuidema, Johan, Petersen, Arjen H., Staal, Mark, Duque, Luisa F., Rodriguez, Sergio, Lathuile, Audrey A. R., Veldhuis, Gert J., Steendam, Rob, Bank, Ruud A., Popa, Eliane R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577552/
https://www.ncbi.nlm.nih.gov/pubmed/25957099
http://dx.doi.org/10.1007/s11095-015-1700-8