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Epididymal research: more warp than weft?

From a review of some aspects of epididymal structure, function and research done largely in my research area over the last 50 years, I conclude that more is known than is understood of sperm maturation and storage in the epididymis. Highly qualified technicians have not always applied sophisticated...

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Autor principal: Cooper, Trevor G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577574/
https://www.ncbi.nlm.nih.gov/pubmed/25652625
http://dx.doi.org/10.4103/1008-682X.146102
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author Cooper, Trevor G
author_facet Cooper, Trevor G
author_sort Cooper, Trevor G
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description From a review of some aspects of epididymal structure, function and research done largely in my research area over the last 50 years, I conclude that more is known than is understood of sperm maturation and storage in the epididymis. Highly qualified technicians have not always applied sophisticated modern techniques in well-considered experiments to physiologically relevant and properly-prepared samples, so that our understanding of the biological problem of the nature of the epididymal epithelial influence on maturing epididymal spermatozoa has not kept pace with the outpouring of data generated, much of which is difficult to interpret. We stand at a crossroads of where to aim our limited resources and personnel: should we continue new technology-led studies in many directions, backtrack to test hypotheses and fill in gaps in our knowledge, or consider more biological directions to our research?
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spelling pubmed-45775742015-09-23 Epididymal research: more warp than weft? Cooper, Trevor G Asian J Androl Experience and History From a review of some aspects of epididymal structure, function and research done largely in my research area over the last 50 years, I conclude that more is known than is understood of sperm maturation and storage in the epididymis. Highly qualified technicians have not always applied sophisticated modern techniques in well-considered experiments to physiologically relevant and properly-prepared samples, so that our understanding of the biological problem of the nature of the epididymal epithelial influence on maturing epididymal spermatozoa has not kept pace with the outpouring of data generated, much of which is difficult to interpret. We stand at a crossroads of where to aim our limited resources and personnel: should we continue new technology-led studies in many directions, backtrack to test hypotheses and fill in gaps in our knowledge, or consider more biological directions to our research? Medknow Publications & Media Pvt Ltd 2015 2015-01-09 /pmc/articles/PMC4577574/ /pubmed/25652625 http://dx.doi.org/10.4103/1008-682X.146102 Text en Copyright: © Asian Journal of Andrology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms
spellingShingle Experience and History
Cooper, Trevor G
Epididymal research: more warp than weft?
title Epididymal research: more warp than weft?
title_full Epididymal research: more warp than weft?
title_fullStr Epididymal research: more warp than weft?
title_full_unstemmed Epididymal research: more warp than weft?
title_short Epididymal research: more warp than weft?
title_sort epididymal research: more warp than weft?
topic Experience and History
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577574/
https://www.ncbi.nlm.nih.gov/pubmed/25652625
http://dx.doi.org/10.4103/1008-682X.146102
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