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Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system
Apelin and its G protein-coupled receptor (GPCR) have emerged as a key signalling pathway in the cardiovascular system. The peptide is a potent inotropic agent and vasodilator. Remarkably, a peptide, Elabela/Toddler, that has little sequence similarity to apelin, has been proposed as a second endoge...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Published By Elsevier In Association With The International Union Of Pharmacology
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577653/ https://www.ncbi.nlm.nih.gov/pubmed/26143239 http://dx.doi.org/10.1016/j.tips.2015.06.002 |