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DNA damage induces nuclear actin filament assembly by Formin-2 and Spire-1/2 that promotes efficient DNA repair

Actin filaments assemble inside the nucleus in response to multiple cellular perturbations, including heat shock, protein misfolding, integrin engagement, and serum stimulation. We find that DNA damage also generates nuclear actin filaments—detectable by phalloidin and live-cell actin probes—with th...

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Detalles Bibliográficos
Autores principales:	Belin, Brittany J, Lee, Terri, Mullins, R Dyche
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577826/ https://www.ncbi.nlm.nih.gov/pubmed/26287480 http://dx.doi.org/10.7554/eLife.07735

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