Cysteinyl leukotrienes mediate lymphokine killer activity induced by NKG2D and IL-15 in cytotoxic T cells during celiac disease

Eicosanoids are inflammatory mediators that play a key but incompletely understood role in linking the innate and adaptive immune systems. Here, we show that cytotoxic effector T cells (CTLs) are capable of both producing and responding to cysteinyl leukotrienes (CystLTs), allowing for the killing o...

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Detalles Bibliográficos
Autores principales: Tang, Fangming, Sally, Benjamin, Lesko, Kathryn, Discepolo, Valentina, Abadie, Valerie, Ciszewski, Cezary, Semrad, Carol, Guandalini, Stefano, Kupfer, Sonia S., Jabri, Bana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577841/
https://www.ncbi.nlm.nih.gov/pubmed/26304964
http://dx.doi.org/10.1084/jem.20150303

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