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Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background

Influenza virus infections represent a serious threat to human health. Both extrinsic and intrinsic factors determine the severity of influenza. The MX dynamin-like GTPase 1 (Mx1) gene has been shown to confer strong resistance to influenza A virus infections in mice. Most laboratory mouse strains,...

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Detalles Bibliográficos
Autores principales:	Shin, Dai-Lun, Hatesuer, Bastian, Bergmann, Silke, Nedelko, Tatiana, Schughart, Klaus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2015
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577889/ https://www.ncbi.nlm.nih.gov/pubmed/26202236 http://dx.doi.org/10.1128/JVI.01305-15

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