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Rapamycin-induced autophagy activity promotes bone fracture healing in rats

Autophagy is a crucial mediating process for normal bone cell function and metabolism in physiology or pathology. Rapamycin has been demonstrated to induce the autophagy pathway by inhibiting the mammalian target of rapamycin (mTOR) pathway. However, the contribution of autophagy in orthopedic disea...

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Detalles Bibliográficos
Autores principales: YANG, GE, DUAN, XUNHONG, LIN, DASHENG, LI, TEN, LUO, DEQING, WANG, LEI, LIAN, KEJIAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577952/
https://www.ncbi.nlm.nih.gov/pubmed/26622487
http://dx.doi.org/10.3892/etm.2015.2660