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Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy

Spinal and bulbar muscular atrophy (SBMA) is a progressive neuromuscular disease caused by polyglutamine expansion in the androgen receptor (AR) protein. Despite extensive research, the exact pathogenic mechanisms underlying SBMA remain elusive. In this study, we present evidence that Nemo-like kina...

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Detalles Bibliográficos
Autores principales: Todd, Tiffany W, Kokubu, Hiroshi, Miranda, Helen C, Cortes, Constanza J, La Spada, Albert R, Lim, Janghoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577982/
https://www.ncbi.nlm.nih.gov/pubmed/26308581
http://dx.doi.org/10.7554/eLife.08493