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Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy
Spinal and bulbar muscular atrophy (SBMA) is a progressive neuromuscular disease caused by polyglutamine expansion in the androgen receptor (AR) protein. Despite extensive research, the exact pathogenic mechanisms underlying SBMA remain elusive. In this study, we present evidence that Nemo-like kina...
Autores principales: | Todd, Tiffany W, Kokubu, Hiroshi, Miranda, Helen C, Cortes, Constanza J, La Spada, Albert R, Lim, Janghoo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577982/ https://www.ncbi.nlm.nih.gov/pubmed/26308581 http://dx.doi.org/10.7554/eLife.08493 |
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