HLA class I is most tightly linked to levels of tapasin compared with other antigen-processing proteins in glioblastoma

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BACKGROUND: Tumour cells can evade the immune system by dysregulation of human leukocyte antigens (HLA-I). Low quantity and/or altered quality of HLA-I cell surface expression is the result of either HLA-I alterations or dysregulations of proteins of the antigen-processing machinery (APM). Tapasin i...

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Detalles Bibliográficos
Autores principales: Thuring, Camilla, Follin, Elna, Geironson, Linda, Freyhult, Eva, Junghans, Victoria, Harndahl, Mikkel, Buus, Søren, Paulsson, Kajsa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578088/
https://www.ncbi.nlm.nih.gov/pubmed/26313662
http://dx.doi.org/10.1038/bjc.2015.297
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