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Identification of Endoglin as an epigenetically regulated tumour-suppressor gene in lung cancer

BACKGROUND: The transforming growth factor-beta (TGF- β) pathway has been implicated in proliferation, migration and invasion of various cancers. Endoglin is a TGF-β accessory receptor that modulates signalling. We identified Endoglin as an epigenetically silenced tumour-suppressor gene in lung canc...

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Detalles Bibliográficos
Autores principales:	O'Leary, K, Shia, A, Cavicchioli, F, Haley, V, Comino, A, Merlano, M, Mauri, F, Walter, K, Lackner, M, Wischnewsky, M B, Crook, T, Lo Nigro, C, Schmid, P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Genetics & Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578092/ https://www.ncbi.nlm.nih.gov/pubmed/26325105 http://dx.doi.org/10.1038/bjc.2015.302

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