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Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report

Nitrogen mustards are chemical agents that are similar to sulfur mustards, with similar toxicities. The present study describes a case of nitrogen mustard-induced acute respiratory failure and myelosuppression in a 33-year-old man. The patient, who was accidentally exposed to nitrogen mustard hydroc...

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Detalles Bibliográficos
Autores principales: ZHANG, XIAOJUAN, ZHANG, ZHIDAN, CHEN, SONG, ZHAO, DONGMEI, ZHANG, FANGXIAO, HU, ZIWEI, XIAO, FENG, MA, XIAOCHUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578113/
https://www.ncbi.nlm.nih.gov/pubmed/26622480
http://dx.doi.org/10.3892/etm.2015.2664
Descripción
Sumario:Nitrogen mustards are chemical agents that are similar to sulfur mustards, with similar toxicities. The present study describes a case of nitrogen mustard-induced acute respiratory failure and myelosuppression in a 33-year-old man. The patient, who was accidentally exposed to nitrogen mustard hydrochloride in a pharmaceutical factory, exhibited severe inhalation injury and respiratory symptoms. Laboratory tests revealed reduced white blood cell counts and lowered platelet levels during the first 6 days after the skin exposure to nitrogen mustard. Following treatment with mechanical ventilation, immunity-enhancing agents and nutritional supplements for 1 month, the patient successfully recovered and was released from hospital.