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Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report

Nitrogen mustards are chemical agents that are similar to sulfur mustards, with similar toxicities. The present study describes a case of nitrogen mustard-induced acute respiratory failure and myelosuppression in a 33-year-old man. The patient, who was accidentally exposed to nitrogen mustard hydroc...

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Autores principales: ZHANG, XIAOJUAN, ZHANG, ZHIDAN, CHEN, SONG, ZHAO, DONGMEI, ZHANG, FANGXIAO, HU, ZIWEI, XIAO, FENG, MA, XIAOCHUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578113/
https://www.ncbi.nlm.nih.gov/pubmed/26622480
http://dx.doi.org/10.3892/etm.2015.2664
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author ZHANG, XIAOJUAN
ZHANG, ZHIDAN
CHEN, SONG
ZHAO, DONGMEI
ZHANG, FANGXIAO
HU, ZIWEI
XIAO, FENG
MA, XIAOCHUN
author_facet ZHANG, XIAOJUAN
ZHANG, ZHIDAN
CHEN, SONG
ZHAO, DONGMEI
ZHANG, FANGXIAO
HU, ZIWEI
XIAO, FENG
MA, XIAOCHUN
author_sort ZHANG, XIAOJUAN
collection PubMed
description Nitrogen mustards are chemical agents that are similar to sulfur mustards, with similar toxicities. The present study describes a case of nitrogen mustard-induced acute respiratory failure and myelosuppression in a 33-year-old man. The patient, who was accidentally exposed to nitrogen mustard hydrochloride in a pharmaceutical factory, exhibited severe inhalation injury and respiratory symptoms. Laboratory tests revealed reduced white blood cell counts and lowered platelet levels during the first 6 days after the skin exposure to nitrogen mustard. Following treatment with mechanical ventilation, immunity-enhancing agents and nutritional supplements for 1 month, the patient successfully recovered and was released from hospital.
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spelling pubmed-45781132015-11-30 Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report ZHANG, XIAOJUAN ZHANG, ZHIDAN CHEN, SONG ZHAO, DONGMEI ZHANG, FANGXIAO HU, ZIWEI XIAO, FENG MA, XIAOCHUN Exp Ther Med Articles Nitrogen mustards are chemical agents that are similar to sulfur mustards, with similar toxicities. The present study describes a case of nitrogen mustard-induced acute respiratory failure and myelosuppression in a 33-year-old man. The patient, who was accidentally exposed to nitrogen mustard hydrochloride in a pharmaceutical factory, exhibited severe inhalation injury and respiratory symptoms. Laboratory tests revealed reduced white blood cell counts and lowered platelet levels during the first 6 days after the skin exposure to nitrogen mustard. Following treatment with mechanical ventilation, immunity-enhancing agents and nutritional supplements for 1 month, the patient successfully recovered and was released from hospital. D.A. Spandidos 2015-10 2015-07-29 /pmc/articles/PMC4578113/ /pubmed/26622480 http://dx.doi.org/10.3892/etm.2015.2664 Text en Copyright: © Zhang et al. This is an open access article distributed under the terms of a Creative Commons Attribution License. http://creativecommons.org/licenses/by/4.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
ZHANG, XIAOJUAN
ZHANG, ZHIDAN
CHEN, SONG
ZHAO, DONGMEI
ZHANG, FANGXIAO
HU, ZIWEI
XIAO, FENG
MA, XIAOCHUN
Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report
title Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report
title_full Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report
title_fullStr Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report
title_full_unstemmed Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report
title_short Nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: A case report
title_sort nitrogen mustard hydrochloride-induced acute respiratory failure and myelosuppression: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578113/
https://www.ncbi.nlm.nih.gov/pubmed/26622480
http://dx.doi.org/10.3892/etm.2015.2664
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