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An improved sequencing-based strategy to estimate locus-specific DNA methylation

BACKGROUND: DNA methylation is an important epigenetic mechanism of transcriptional control that plays an essential role in several cellular functions. Aberrant DNA methylation in cancer has been frequently associated with downregulation of microRNAs and protein coding genes, such as miR-200c/miR-14...

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Detalles Bibliográficos
Autores principales:	Brisotto, Giulia, di Gennaro, Alessandra, Damiano, Valentina, Armellin, Michela, Perin, Tiziana, Maestro, Roberta, Santarosa, Manuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578270/ https://www.ncbi.nlm.nih.gov/pubmed/26391005 http://dx.doi.org/10.1186/s12885-015-1646-6

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