Design and synthesis of hybrid cyclophanes containing thiophene and indole units via Grignard reaction, Fischer indolization and ring-closing metathesis as key steps

We demonstrate a new synthetic strategy to cyclophanes containing thiophene and indole moieties via Grignard addition, Fischer indolization and ring-closing metathesis as key steps.

Detalles Bibliográficos
Autores principales: Kotha, Sambasivarao, Chinnam, Ajay Kumar, Shirbhate, Mukesh Eknathrao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578400/
https://www.ncbi.nlm.nih.gov/pubmed/26425209
http://dx.doi.org/10.3762/bjoc.11.165
Descripción
Sumario:We demonstrate a new synthetic strategy to cyclophanes containing thiophene and indole moieties via Grignard addition, Fischer indolization and ring-closing metathesis as key steps.

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