Cargando…

A new and efficient procedure for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones

A new and efficient method for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones in one step with high yields from the reaction of lawsone with 1,3,5-triazinanes was developed.

Detalles Bibliográficos
Autores principales:	Reis, Marcelo Isidoro P, Campos, Vinícius R, Resende, Jackson A L C, Silva, Fernando C, Ferreira, Vitor F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2015
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578459/ https://www.ncbi.nlm.nih.gov/pubmed/26425181 http://dx.doi.org/10.3762/bjoc.11.137

Ejemplares similares

Synthesis and Antimicrobial Evaluation of 1,4‐Naphthoquinone Derivatives as Potential Antibacterial Agents
por: Ravichandiran, Palanisamy, et al.
Publicado: (2019)

Synthesis and Evaluation of Antimicrobial and Cytotoxic Activity of Oxathiine-Fused Quinone-Thioglucoside Conjugates of Substituted 1,4-Naphthoquinones
por: Sabutski, Yuri E., et al.
Publicado: (2020)

Synthetic 1,4-Pyran Naphthoquinones Are Potent Inhibitors of Dengue Virus Replication
por: da Costa, Emmerson C. B., et al.
Publicado: (2013)

New Pyrimidinone-Fused 1,4-Naphthoquinone Derivatives Inhibit the Growth of Drug Resistant Oral Bacteria
por: Kim, Kyungmin, et al.
Publicado: (2020)

2-Phenyl-2-(pyridin-2-yl)hexahydropyrimidine
por: Jayaratna, Naleen B., et al.
Publicado: (2010)

Anti-Herpetic, Anti-Dengue and Antineoplastic Activities of Simple and Heterocycle-Fused Derivatives of Terpenyl-1,4-Naphthoquinone and 1,4-Anthraquinone †
por: Roa-Linares, Vicky C., et al.
Publicado: (2019)

Mechanism of the Fe(iii)-catalyzed synthesis of hexahydropyrimidine with α-phenylstyrene: a DFT study
por: Cheng, Yaxuan, et al.
Publicado: (2022)

2-Methyl-2-(2-pyridyl)hexahydropyrimidine
por: Al-Resayes, Saud
Publicado: (2009)

In Vitro Antifungal Activity of Hexahydropyrimidine Derivatives against the Causative Agents of Dermatomycosis
por: Martins, Francislene J., et al.
Publicado: (2017)

Dual targeting of the cancer antioxidant network with 1,4-naphthoquinone fused Gold(i) N-heterocyclic carbene complexes
por: McCall, R., et al.
Publicado: (2017)

Chemoselective Synthesis of Mannich Adducts from 1,4-Naphthoquinones and Profile as Autophagic Inducers in Oral Squamous Cell Carcinoma
por: Borges, Amanda A., et al.
Publicado: (2022)

Conversion of Hydroxyproline “Doubly Customizable Units” to Hexahydropyrimidines: Access to Conformationally Constrained Peptides
por: Hernández, Dácil, et al.
Publicado: (2023)

1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis
por: Ribeiro, Ruan Carlos B, et al.
Publicado: (2022)

Optimization of 1,4-Naphthoquinone Hit Compound: A Computational, Phenotypic, and In Vivo Screening against Trypanosoma cruzi
por: Lara, Leonardo S., et al.
Publicado: (2021)

2-[2-Chloro-5-(trifluoromethyl)phenyl]hexahydropyrimidine monohydrate
por: Fun, Hoong-Kun, et al.
Publicado: (2008)

Exploring the Antimicrobial and Antitumoral Activities of Naphthoquinone-Grafted Chitosans
por: Pauli, Fernanda Petzold, et al.
Publicado: (2023)

The tert-amino effect in heterocyclic chemistry: Synthesis of new fused pyrazolinoquinolizine and 1,4-oxazinopyrazoline derivatives
por: Prajapati, Dipak, et al.
Publicado: (2007)

5-Hydroxy-8-nitro-1,4-naphthoquinone
por: Tan, Daniel Teoh-Chuan, et al.
Publicado: (2008)

Sustainable Synthesis, Antiproliferative and Acetylcholinesterase Inhibition of 1,4- and 1,2-Naphthoquinone Derivatives
por: Cabral, Rafaela G., et al.
Publicado: (2023)

Efficient access to β-vinylporphyrin derivatives via palladium cross coupling of β-bromoporphyrins with N-tosylhydrazones
por: Campos, Vinicius R, et al.
Publicado: (2017)

Novel Solid Dispersions of Naphthoquinone Using Different Polymers for Improvement of Antichagasic Activity
por: da Silva Oliveira, Verônica, et al.
Publicado: (2020)

Formation of 5-Hydroxy-3-methoxy-1,4-naphthoquinone and 8-Hydroxy-4-methoxy-1,2-naphthoquinone from Juglone
por: Blauenburg, Bastian, et al.
Publicado: (2012)

Insights into cytochrome bc (1) complex binding mode of antimalarial 2-hydroxy-1,4-naphthoquinones through molecular modelling
por: Sodero, Ana Carolina Rennó, et al.
Publicado: (2017)

2-Chloro-3-(4-chlorobenzamido)-1,4-naphthoquinone
por: Brandy, Yakini, et al.
Publicado: (2008)

Aromatase inhibitory activity of 1,4-naphthoquinone derivatives and QSAR study
por: Prachayasittikul, Veda, et al.
Publicado: (2017)

Flow Injection Analysis Coupled with Carbon Electrodes as the Tool for Analysis of Naphthoquinones with Respect to Their Content and Functions in Biological Samples
por: Babula, Petr, et al.
Publicado: (2006)

Hybrids of 1,4-Naphthoquinone with Thymidine Derivatives: Synthesis, Anticancer Activity, and Molecular Docking Study
por: Kadela-Tomanek, Monika, et al.
Publicado: (2023)

Potential of 2-Hydroxy-3-Phenylsulfanylmethyl-[1,4]-Naphthoquinones against Leishmania (L.) infantum: Biological Activity and Structure-Activity Relationships
por: Pinto, Erika G., et al.
Publicado: (2014)

The diverse mechanisms and anticancer potential of naphthoquinones
por: Pereyra, Carolina Escardó, et al.
Publicado: (2019)

Thermally Induced Synthesis of Anthracene‐, Pyrene‐ and Naphthalene‐Fused Porphyrins
por: Pijeat, Joffrey, et al.
Publicado: (2021)

Synthesis and evaluation of photophysical, electrochemical, and ROS generation properties of new chalcogen-naphthoquinones-1,2,3-triazole hybrids
por: Gomes, Luana S., et al.
Publicado: (2023)

The Effects of 1,4-Naphthoquinone (NQ) and Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone, DHNQ) Individually and in Combination on Growth and Oxidative Stress in Maize (Zea mays L.) Seedlings
por: Karcz, Waldemar, et al.
Publicado: (2023)

Synthesis of the Benzo-fused Indolizidine Alkaloid Mimics
por: Comins, Daniel L, et al.
Publicado: (2007)

5-Chloro-8-hydroxy-6-methyl-1,4-naphthoquinone
por: Tan, Daniel Teoh-Chuan, et al.
Publicado: (2009)

1,4-Naphthoquinones: From Oxidative Damage to Cellular and Inter-Cellular Signaling
por: Klotz, Lars-Oliver, et al.
Publicado: (2014)

1,4-Naphthoquinone Analogues: Potent Antibacterial Agents and Mode of Action Evaluation
por: Ravichandiran, Palanisamy, et al.
Publicado: (2019)

Evaluation of 1,4-naphthoquinone derivatives as antibacterial agents: activity and mechanistic studies
por: Liu, Zhizhuo, et al.
Publicado: (2022)

Synthesis, Leishmanicidal Activity and Theoretical Evaluations of a Series of Substituted bis-2-Hydroxy-1,4-Naphthoquinones
por: de Araújo, Morgana V., et al.
Publicado: (2014)

Synthesis, SAR, and Docking Studies Disclose 2-Arylfuran-1,4-naphthoquinones as In Vitro Antiplasmodial Hits
por: Borgati, Tatiane Freitas, et al.
Publicado: (2017)

Synthesis and Biological Evaluation of Lipophilic 1,4-Naphthoquinone Derivatives against Human Cancer Cell Lines
por: Wang, Shao-Hung, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ngjmhm2uepo8eo8ulegh5nk0fd