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Amaranthus leucocarpus lectin recognizes a moesin-like O-glycoprotein and costimulates murine CD3-activated CD4(+) T cells

The Galβ1,3GalNAcα1,O-Ser/Thr specific lectin from Amaranthus leucocarpus (ALL) binds a ∼70 kDa glycoprotein on murine T cell surface. We show that in the absence of antigen presenting cells, murine CD4(+) T cells activated by an anti-CD3 antibody plus ALL enhanced cell proliferation similar to thos...

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Detalles Bibliográficos
Autores principales: Arenas-Del Ángel, Maria, Legorreta-Herrera, Martha, Mendoza-Hernández, Guillermo, Garfias, Yonathan, Chávez, Raul, Zenteno, Edgar, Lascurain, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578519/
https://www.ncbi.nlm.nih.gov/pubmed/26417436
http://dx.doi.org/10.1002/iid3.58