Overexpression of Fkbp11, a feature of lupus B cells, leads to B cell tolerance breakdown and initiates plasma cell differentiation

Systemic Lupus Erythematosus (SLE) is a severe systemic autoimmune disease, characterized by multi-organ damages, triggered by an autoantibody-mediated inflammation, and with a complex genetic influence. It is today accepted that adult SLE arises from the building up of many subtle gene variations,...

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Detalles Bibliográficos
Autores principales: Ruer-Laventie, Julie, Simoni, Léa, Schickel, Jean-Nicolas, Soley, Anne, Duval, Monique, Knapp, Anne-Marie, Marcellin, Luc, Lamon, Delphine, Korganow, Anne-Sophie, Martin, Thierry, Pasquali, Jean-Louis, Soulas-Sprauel, Pauline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578525/
https://www.ncbi.nlm.nih.gov/pubmed/26417441
http://dx.doi.org/10.1002/iid3.65

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