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Isocitrate dehydrogenase mutations: new opportunities for translational research

Over the last decade, comprehensive genome-wide sequencing studies have enabled us to find out unexpected genetic alterations of metabolism in cancer. An example is the identification of arginine missense mutations of isocitrate dehydrogenases-1 and -2 (IDH1/2) in glioma, acute myeloid leukemia (AML...

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Detalles Bibliográficos
Autores principales:	Keum, Young-Sam, Choi, Bu Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2015
Materias:	Contributed Mini Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578565/ https://www.ncbi.nlm.nih.gov/pubmed/25787993 http://dx.doi.org/10.5483/BMBRep.2015.48.5.021

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