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Insulin activates EGFR by stimulating its interaction with IGF-1R in low-EGFR-expressing TNBC cells
The expression of epidermal growth factor receptor (EGFR) is an important diagnostic marker for triple-negative breast cancer (TNBC) cells, which lack three hormonal receptors: estrogen and progesterone receptors as well as epidermal growth factor receptor 2. EGFR transactivation can cause drug resi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578621/ https://www.ncbi.nlm.nih.gov/pubmed/25341922 http://dx.doi.org/10.5483/BMBRep.2015.48.6.157 |