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Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging
Kasabach-Merritt phenomenon (KMP) is characterized by vascular tumour and consumptive coagulopathy with life-threatening thrombocytopenia, prolonged prothrombin time and partial thromboplastin time, hypofibrinogenemia, and the presence of high fibrin split products. We report a case of 3-year-old bo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578750/ https://www.ncbi.nlm.nih.gov/pubmed/26435870 http://dx.doi.org/10.1155/2015/537530 |
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author | Keskindemirci, Gonca Tuğcu, Deniz Aydoğan, Gönül Akçay, Arzu Aktay Ayaz, Nuray Er, Ali Yekeler, Ensar Bilgiç, Bilge |
author_facet | Keskindemirci, Gonca Tuğcu, Deniz Aydoğan, Gönül Akçay, Arzu Aktay Ayaz, Nuray Er, Ali Yekeler, Ensar Bilgiç, Bilge |
author_sort | Keskindemirci, Gonca |
collection | PubMed |
description | Kasabach-Merritt phenomenon (KMP) is characterized by vascular tumour and consumptive coagulopathy with life-threatening thrombocytopenia, prolonged prothrombin time and partial thromboplastin time, hypofibrinogenemia, and the presence of high fibrin split products. We report a case of 3-year-old boy with local aggressive vascular lesions associated with KMP. Magnetic resonance imaging revealed an extensive lesion at paravertebral and retroperitoneal regions that was infiltrating vertebrae. Although we did not get any response to steroid or propranolol treatment, partial response was observed radiologically with interferon-alpha treatment. Unfortunately, the patient died because of the uncontrolled consumptive coagulopathy that led to intracranial hemorrhage which was caused by huge knee hematoma after minor trauma. |
format | Online Article Text |
id | pubmed-4578750 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-45787502015-10-04 Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging Keskindemirci, Gonca Tuğcu, Deniz Aydoğan, Gönül Akçay, Arzu Aktay Ayaz, Nuray Er, Ali Yekeler, Ensar Bilgiç, Bilge Case Rep Pediatr Case Report Kasabach-Merritt phenomenon (KMP) is characterized by vascular tumour and consumptive coagulopathy with life-threatening thrombocytopenia, prolonged prothrombin time and partial thromboplastin time, hypofibrinogenemia, and the presence of high fibrin split products. We report a case of 3-year-old boy with local aggressive vascular lesions associated with KMP. Magnetic resonance imaging revealed an extensive lesion at paravertebral and retroperitoneal regions that was infiltrating vertebrae. Although we did not get any response to steroid or propranolol treatment, partial response was observed radiologically with interferon-alpha treatment. Unfortunately, the patient died because of the uncontrolled consumptive coagulopathy that led to intracranial hemorrhage which was caused by huge knee hematoma after minor trauma. Hindawi Publishing Corporation 2015 2015-09-08 /pmc/articles/PMC4578750/ /pubmed/26435870 http://dx.doi.org/10.1155/2015/537530 Text en Copyright © 2015 Gonca Keskindemirci et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Keskindemirci, Gonca Tuğcu, Deniz Aydoğan, Gönül Akçay, Arzu Aktay Ayaz, Nuray Er, Ali Yekeler, Ensar Bilgiç, Bilge Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging |
title | Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging |
title_full | Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging |
title_fullStr | Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging |
title_full_unstemmed | Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging |
title_short | Paravertebral and Retroperitoneal Vascular Tumour Presenting with Kasabach-Merritt Phenomenon in Childhood, Diagnosed with Magnetic Resonance Imaging |
title_sort | paravertebral and retroperitoneal vascular tumour presenting with kasabach-merritt phenomenon in childhood, diagnosed with magnetic resonance imaging |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578750/ https://www.ncbi.nlm.nih.gov/pubmed/26435870 http://dx.doi.org/10.1155/2015/537530 |
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