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Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism
PPARγ (peroxisome proliferator activated receptor γ) is a ligand activated transcription factor of the nuclear receptor superfamily that controls the expression of a variety of genes involved in fatty acid metabolism, adipogenesis, and insulin sensitivity. While endogenous ligands of PPARγ include f...
Autores principales: | Kroker, Alice J., Bruning, John B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578752/ https://www.ncbi.nlm.nih.gov/pubmed/26435709 http://dx.doi.org/10.1155/2015/816856 |
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