Family Perception and 6-Month Symptomatic and Functioning Outcomes in Young Adolescents at Clinical High Risk for Psychosis in a General Population in China

BACKGROUND AND AIMS: Given the difficulty of treating schizophrenia and other forms of psychosis, researchers have shifted focus to early detection and intervention of individuals at clinical high risk (CHR) for psychosis. Previous studies have shown that elements in family functioning could predict...

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Autores principales: Wang, Lu, Shi, JingYu, Chen, FaZhan, Yao, YuHong, Zhan, ChenYu, Yin, XiaoWen, Fang, XiaoYan, Wang, HaoJie, Yuan, JiaBei, Zhao, XuDong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578854/
https://www.ncbi.nlm.nih.gov/pubmed/26394221
http://dx.doi.org/10.1371/journal.pone.0138361
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author Wang, Lu
Shi, JingYu
Chen, FaZhan
Yao, YuHong
Zhan, ChenYu
Yin, XiaoWen
Fang, XiaoYan
Wang, HaoJie
Yuan, JiaBei
Zhao, XuDong
author_facet Wang, Lu
Shi, JingYu
Chen, FaZhan
Yao, YuHong
Zhan, ChenYu
Yin, XiaoWen
Fang, XiaoYan
Wang, HaoJie
Yuan, JiaBei
Zhao, XuDong
author_sort Wang, Lu
collection PubMed
description BACKGROUND AND AIMS: Given the difficulty of treating schizophrenia and other forms of psychosis, researchers have shifted focus to early detection and intervention of individuals at clinical high risk (CHR) for psychosis. Previous studies have shown that elements in family functioning could predict symptom outcome in CHR individuals. However, associations between self reported family functioning and symptom or functioning outcome of CHR individuals was rarely reported. Our study aimed to investigate the characteristics and the role of family functioning in the development of CHR individuals among young adolescents. METHODS: A sample of 32 CHR individuals was recruited from 2800 university students. The characteristics of family perception were evaluated by both Family Assessment Device (FAD) and Family cohesion and adaptability evaluation Scale II (FACES II). 6 month follow up data was available with 25 of the recruited CHR individuals. Baseline socio-demographic characteristics and family functioning were compared between CHR and control group. We also measured the associations between different dimensions of perceived family functioning and both severity of prodromal symptoms and global functioning at baseline and 6-month follow up. RESULTS: CHR individuals showed more maladaptive family functioning compared to control in nearly all of the dimensions of FAD and FACES II except for Affective Involvement. Better Problem Solving and Affective Responsiveness predicted less severe positive and negative symptoms respectively. Family cohesion and adaptability were not only correlated with the baseline severity of general symptoms, but also positively associated with the general and disorganized symptom outcome. CONCLUSIONS: This study contributed preliminary evidence towards the associations between family perception and symptom outcome of CHR individuals. It also provided evidence for the importance of family interventions on CHR individuals.
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spelling pubmed-45788542015-10-01 Family Perception and 6-Month Symptomatic and Functioning Outcomes in Young Adolescents at Clinical High Risk for Psychosis in a General Population in China Wang, Lu Shi, JingYu Chen, FaZhan Yao, YuHong Zhan, ChenYu Yin, XiaoWen Fang, XiaoYan Wang, HaoJie Yuan, JiaBei Zhao, XuDong PLoS One Research Article BACKGROUND AND AIMS: Given the difficulty of treating schizophrenia and other forms of psychosis, researchers have shifted focus to early detection and intervention of individuals at clinical high risk (CHR) for psychosis. Previous studies have shown that elements in family functioning could predict symptom outcome in CHR individuals. However, associations between self reported family functioning and symptom or functioning outcome of CHR individuals was rarely reported. Our study aimed to investigate the characteristics and the role of family functioning in the development of CHR individuals among young adolescents. METHODS: A sample of 32 CHR individuals was recruited from 2800 university students. The characteristics of family perception were evaluated by both Family Assessment Device (FAD) and Family cohesion and adaptability evaluation Scale II (FACES II). 6 month follow up data was available with 25 of the recruited CHR individuals. Baseline socio-demographic characteristics and family functioning were compared between CHR and control group. We also measured the associations between different dimensions of perceived family functioning and both severity of prodromal symptoms and global functioning at baseline and 6-month follow up. RESULTS: CHR individuals showed more maladaptive family functioning compared to control in nearly all of the dimensions of FAD and FACES II except for Affective Involvement. Better Problem Solving and Affective Responsiveness predicted less severe positive and negative symptoms respectively. Family cohesion and adaptability were not only correlated with the baseline severity of general symptoms, but also positively associated with the general and disorganized symptom outcome. CONCLUSIONS: This study contributed preliminary evidence towards the associations between family perception and symptom outcome of CHR individuals. It also provided evidence for the importance of family interventions on CHR individuals. Public Library of Science 2015-09-22 /pmc/articles/PMC4578854/ /pubmed/26394221 http://dx.doi.org/10.1371/journal.pone.0138361 Text en © 2015 Wang et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Wang, Lu
Shi, JingYu
Chen, FaZhan
Yao, YuHong
Zhan, ChenYu
Yin, XiaoWen
Fang, XiaoYan
Wang, HaoJie
Yuan, JiaBei
Zhao, XuDong
Family Perception and 6-Month Symptomatic and Functioning Outcomes in Young Adolescents at Clinical High Risk for Psychosis in a General Population in China
title Family Perception and 6-Month Symptomatic and Functioning Outcomes in Young Adolescents at Clinical High Risk for Psychosis in a General Population in China
title_full Family Perception and 6-Month Symptomatic and Functioning Outcomes in Young Adolescents at Clinical High Risk for Psychosis in a General Population in China
title_fullStr Family Perception and 6-Month Symptomatic and Functioning Outcomes in Young Adolescents at Clinical High Risk for Psychosis in a General Population in China
title_full_unstemmed Family Perception and 6-Month Symptomatic and Functioning Outcomes in Young Adolescents at Clinical High Risk for Psychosis in a General Population in China
title_short Family Perception and 6-Month Symptomatic and Functioning Outcomes in Young Adolescents at Clinical High Risk for Psychosis in a General Population in China
title_sort family perception and 6-month symptomatic and functioning outcomes in young adolescents at clinical high risk for psychosis in a general population in china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578854/
https://www.ncbi.nlm.nih.gov/pubmed/26394221
http://dx.doi.org/10.1371/journal.pone.0138361
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