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c-Myc Represses Tumor-Suppressive microRNAs, let-7a, miR-16 and miR-29b, and Induces Cyclin D2-Mediated Cell Proliferation in Ewing’s Sarcoma Cell Line

Myc oncogenic transcription factor is known to inhibit tumor suppressive microRNAs (miRNAs), resulting in greater expression of their target protein related to cell cycle, invasion or anti-apoptotic factors in human cancer cells. To explore possible oncogenic factors in Ewing’s sarcoma (ES), we cond...

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Detalles Bibliográficos
Autores principales: Kawano, Masanori, Tanaka, Kazuhiro, Itonaga, Ichiro, Iwasaki, Tatsuya, Tsumura, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578885/
https://www.ncbi.nlm.nih.gov/pubmed/26393798
http://dx.doi.org/10.1371/journal.pone.0138560