Leukocyte Mitochondrial DNA Copy Number Is Associated with Chronic Obstructive Pulmonary Disease

BACKGROUND: Oxidative stress is known to be involved in the pathogenesis of chronic obstructive pulmonary disease (COPD). Evidence suggests that leukocytes mitochondria DNA (mtDNA) is susceptible to undergo mutations, insertions, or depletion in response to reactive oxidative stress (ROS). We hypoth...

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Detalles Bibliográficos
Autores principales: Liu, Shih-Feng, Kuo, Ho-Chang, Tseng, Ching-Wan, Huang, Hung-Tu, Chen, Yung-Che, Tseng, Chia-Cheng, Lin, Meng-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578933/
https://www.ncbi.nlm.nih.gov/pubmed/26394041
http://dx.doi.org/10.1371/journal.pone.0138716

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