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Automated Identification of Core Regulatory Genes in Human Gene Regulatory Networks

Human gene regulatory networks (GRN) can be difficult to interpret due to a tangle of edges interconnecting thousands of genes. We constructed a general human GRN from extensive transcription factor and microRNA target data obtained from public databases. In a subnetwork of this GRN that is active d...

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Detalles Bibliográficos
Autores principales:	Narang, Vipin, Ramli, Muhamad Azfar, Singhal, Amit, Kumar, Pavanish, de Libero, Gennaro, Poidinger, Michael, Monterola, Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578944/ https://www.ncbi.nlm.nih.gov/pubmed/26393364 http://dx.doi.org/10.1371/journal.pcbi.1004504

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